This page is about the hormone therapy Casodex (bicalutamide) that is a treatment for advanced prostate cancer.

Prostate cancer depends on the male sex hormone, testosterone, to grow. Testosterone is a type of hormone called an androgen. Bicalutamide is an anti-androgen. It stops testosterone reaching the cancer cells. This can shrink the cancer or slow its growth. Casodex is not a cure or treatment for prostate cancer but with Lupron, can add in slowing down the cancer and making it more susceptible to radiation therapy.

You may have a few side effects. They may be mild or more severe. A side effect may get better or worse through your course of treatment. Or more side effects may develop as the course goes on.

The side effects may be different if you are having bicalutamide with other medicines.

Common Side Effects

  • A low sex drive (low libido) affects most men.
  • Hot flushes and sweats affect about 50% of men. Unfortunately some men have them for as long as they stay on treatment.
  • Breast tenderness and swelling – this can affect about 40% of men and can be distressing.
  • Problems getting an erection (impotence).
  • About 30% of men have general body pain.
  • Feeling sick or being sick affects about 10% of men. This is usually mild and can be controlled by anti sickness tablets.
  • Feeling weak.
  • Dizziness – don’t drive or operate machinery if you have this side effect.
  • A skin rash or dry skin and itching.
  • Constipation – drink plenty of fluids.
  • Blood in your urine.