Lupron is a hormone therapy.  Lupron  is classified as an “LHRH agonist.”

What Lupron Depot Is Used For:

  • Prostate cancer
  • Breast, ovarian and endometrial cancer
  • Also used in non-cancerous conditions such as endometriosis, infertility, benign prostatic hypertrophy (BPH).

How Lupron Depot Is Given:

  • As an injection under the skin (subcutaneous, SubQ), or into the muscle (intramuscular, IM).
  • May be given as a daily, monthly, or every 3 or 4month injection depending on the formulation and condition being treated.
  • Also may be given as a once-a-year implantable device (Viadur(tm)).
  • There is no pill form of Lupron Depot.
  • Your doctor will determine your dose and schedule.

Lupron Side Effects:

The following Lupron side effects are common for patients taking Lupron:

  • Hot flashes
  • Decreased libido (loss of interest in sex)
  • Impotence (inability to obtain or sustain an erection)

These Lupron Depot side effects are less common side effects of patients receiving Lupron Depot:

  • Increased bone pain or urinary retention due to disease “flare” during first couple weeks of treatment.
  • Breast pain
  • Discomfort at injection site
  • Blood test abnormalities – increased cholesterol levels
  • Swelling of feet or ankles (edema)
  • Weakness -general loss of strength
  • Swelling of the breasts (gynecomastia)
  • Depression
  • Sweating